Jump to content

Longjohn

Members
  • Posts

    47,666
  • Joined

  • Last visited

  • Days Won

    295
  • Country

    United States

Longjohn last won the day on November 18 2023

Longjohn had the most liked content!

3 Followers

About Longjohn

  • Birthday 09/18/1949

Profile Information

  • Gender
    Male
  • Location
    Western Pa.
  • Interests
    Cycling, crashing, kayaking, fishing, fitness

Profile Fields

  • Bike(s)
    Trek 1,000, Trek 520, Lynskey GR300

Recent Profile Visitors

12,947 profile views

Longjohn's Achievements

Flahute

Flahute (7/9)

  • Dedicated
  • Posting Machine
  • Collaborator
  • First Post
  • Conversation Starter

Recent Badges

62,959

Reputation

57

Community Answers

  1. How did I miss this? Where is the link? I’ve been concerned about you two. I know from experience that age has a big effect on how fast and how well your body heals after a crash. I watch young people crash and go head over heels for hundreds of feet and get up like nothing ever happened. Then I wonder if I could even survive that crash? I know my bones break a lot easier than they used to.
  2. The problem with the chocolate cigars is I could never keep them lit.
  3. Looks like good and plenty use the real thing. Ingredients: Sugar, corn syrup, enriched wheat flour (flour, niacin, ferrous sulfate, thiamin, mononitrate, riboflavin, and folic acid), molasses, contains 2% or less of: artificial color (k-carmine, red 40 lake), gum acacia, licorice extract: modified cornstarch, salt, caramel color, resinous glaze, carnauba wax, anise oil, natural and artificial flavor, sulfur dioxide, to maintain freshness.
  4. One of the guys I worked with was a big time hunter. He shot a wild bore and had the hams smoked. He brought one into work to share. It tasted like regular ham.
  5. More than you wanted to know: than 0.2 g/100 g; yrs, years Go to: Discussion Licorice toxicity is characterized by the symptom triad of hypertension, hypokalemia, and metabolic alkalosis—so-called pseudohyperaldosteronism. Marked rhabdomyolysis/paresis, cardiac complications, acute hypertension (including posterior reversible encephalopathy syndrome, PRES), acute renal failure, and respiratory failure have been described as severe manifestations, and eight deaths have been reported. In addition to eating licorice candies, the given causes include the use of herbal medicine preparations, chewing tobacco, and drinking tea and alcoholic beverages. In the majority of cases, there was chronic consumption; individual cases of acute intoxication due to large amounts of licorice have also been described. The active ingredient in licorice is glycyrrhizin, which is converted to 3ß-monoglucuronyl-18ß-glycyrrhetinic acid (3MGA) and 18ß-glycyrrhetinic acid (GA) in the gut. These active metabolites inhibit the 11ß-hydroxysteroid dehydrogenase type II enzyme (11ß-HSD2) and prevent the conversion of cortisol to cortisone. Unlike cortisone, cortisol binds to the mineralocorticoid receptor. This cortisol excess leads to increased potassium and proton excretion as well as to sodium and water retention, with increased systemic resistance. The triad of symptoms typical of classic hyperaldosteronism (Conn’s syndrome) results from the aldosterone-like effect: hypokalemia, hypertension, and metabolic alkalosis (3). In licorice toxicity, the aldosterone and renin levels are normal or suppressed, the cortisol-to-cortisone ratio in the peripheral venous blood is greatly increased. The diagnosis of these laboratory values also serves in particular to distinguish intoxication from possible differential diagnoses in the case of a licorice intake of questionable relevance; these include Conn’s syndrome, Cushing’s disease, and renal artery stenosis. Additionally, apparent mineralocorticoid excess (AME) syndrome presents similar laboratory values; however, it usually stems from a deletion in the HSD11B2 gene (16q22) and often manifests in childhood (4). Hypokalemia can lead to cardiac arrhythmia and rhabdomyolysis, which in turn can lead to tetraplegia and paralysis of the respiratory muscles. Myoglobinuria can trigger acute renal failure. Potassium replacement and lowering high blood pressure are the relevant emergency measures. After samples for hormone diagnostics are taken, administration of mineralocorticoid receptor-blocking agents is particularly effective (e.g., spironolactone or eplerenone). In the majority of our cases, hypertension had previously been insufficiently controlled by medication. In all of our cases, all symptoms were reversible after cessation of licorice consumption, and the antihypertensive medication started previously could be reduced or discontinued. Nevertheless, fatal outcomes are also described in the literature. Toxic effects of licorice consumption occur in certain collectives (including in persons with pre-existing arterial hypertension, presumably due to reduced 11ß-HSD2 activity) even at amounts perceived as being harmless. Loop and thiazide diuretics may potentiate the potassium lowering effects of licorice (of note, four of our patients had been previously medicated with thiazide). Patients with delayed gastrointestinal transit or with anorexia are also at greater risk because of the lower ingestion levels required for toxicity (5). In principle, the study situation on safe dose recommendations is insufficient, and non-daily consumption is also not shown in the available studies. With this article, we would like draw attention to an underdiagnosed clinical entity that has significant implications for certain risk groups. Clear risk information and clearer labeling of the relevant products – including inclusion in the package inserts for medications – are desirable. Although the health risks associated with the consumption of licorice products have been known since the 1960s, the case reports published in Europe and internationally show that there is still a need for information. Licorice consumption may also play a role in some patients with regard to chronic hypertension, and physicians should therefore specifically ask about it.
  6. A lot of stuff can kill you if taken in too large a quantity but they are still allowed to sell it. The thing is you need to know the risks and consume responsibly. Hershey’s apparently didn’t have a warning label on their licorice .
  7. Black licorice seems to have made somewhat of a comeback after it just about disappeared when I was a kid. They changed to a black chewy anise flavored licorice after the health risks of regular licorice were determined. When I used to deliver steel to the port of Baltimore there was a very large building across the bay that said something like National licorice company. I asked the guy who was unloading my truck if that big building actually just did licorice and he said not anymore. They went out of business after it was discovered that you can’t make licorice that isn’t toxic if it is consumed in large quantities. Anise flavored licorice kinda/sorta tastes like licorice but it’s like replacing coffee with decaf. It just doesn’t cut the mustard. This post is from my memory and I might not have all the facts straight but licorice has been known to cause health problems for a very long time.
  8. But the church camp I worked at got free peanuts, peanut butter, peanut oil, and peanut shortening.
  9. It will be ok if you use something like a butter crème to ice it but it will make your shoulder very sticky.
  10. Send it to LAJ, you stored his crap long enough. He owes you.
  11. Where is Dr. Mickin’s thoughts on this? @MickinMD Where are you?
  12. Two for you and one for me.
×
×
  • Create New...